Guidance for HTA-licensed organisations on the recent chikungunya virus outbreak in Italy
The European Centre for Disease Prevention and Control (ECDC) has produced a rapid risk assessment concerning the clusters of autochthonous chikungunya cases in Italy (Anzio and Rome). The risk assessment has recommended that measures should be taken to prevent the transmission of chikungunya through substances of human origin.
Establishments in the human application and organ donation and transplantation sectors should review their donor selection procedures accordingly.
Up to date information on chikungunya and a copy of the risk assessment can be found on the ECDC website.
The first update of the Chikungunya in Italy Risk Assessment has been published by ECDC and can be found here (PDF).
Donors of tissues and cells and organs must be excluded from donating where there is evidence of risk factors for transmissible diseases on the basis of a risk assessment, taking into consideration donor travel and exposure history and local infectious disease prevalence.
We recommend that establishments should follow the advice provided by the advisory bodies relevant to the sector in which they operate.
The Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee (JPAC) have updated the Geographical Disease Risk Index (GDRI) entry for Italy. The JPAC donor selection guidelines and associated exclusions for tropical viruses, including chikungunya virus, therefore currently apply to donors who have visited Rome and the surrounding region of Lazio, including the Vatican City, Anzio and Latina.